Air supremacy including land supremacy depends on equipment and weapons researched and developed with superior engineering knowledge, design and practice. There is the analytical and computational part, as well as the essential product realization portion. Superiority in engineering knowledge and practice is requisite. There are also telltale clues from the lyrics of national anthems, which may speak of a nation’s desire for military superiority, or at least of being undaunted by military conflict to maintain a nation’s independence. Airborne drones are being recognized as being essential for air supremacy in the twenty-first century, and are the focus of this article. The technology of airborne drones rests on the shoulders of aircraft technology, on robotics and computer technology, especially at the micro-scale end of fast and powerful computers. This work is focused on the research and development required to maintain/ acquire air supremacy in this twenty-first century, so that military conflicts need not drag on. Numerous lives can be spared as a consequence.