On the basis of piezoelectric effect of PVDF film, the flexible thin film single-point force sensor with total dimension 75mmx20mmx1mm is devised to dynamically measure single-point force in biomedical or mechanical field. New flat interlayer structure with cavum is firstly introduced to enlarge the deformation of PVDF thin film, and a conductive supporting rack is firstly utilized to construct a detecting cavum and to realize the connection between PVDF film and down conductive electrode. Such structure is flat as the traditional sandwich structure; but its cavum may make sensor have a sensitive reaction and larger measurement range. Its measurement range is from 0 to 6217N and it works between -40°C and 80°C. The total thickness 1mm is so thin that the given sensor can be easily placed into aperture. Results of experiment and analysis illustrate that the developed sensor is available and that it may be used to dynamically sense a single-point force. The flat interlayer structure given is thin and flexible and flat and implantable. Such sensor makes that it becomes possible to dynamically measure single-point force in mechanical field or biomedical field.