3D microscopic cutting simulation of CFRP is very important for revealing material removal mechanism and damage suppression, wherein mass scaling is usually adopted for solving the problem of extremely low calculating efficiency. For the simulation with very low cutting speed, a quasi-static criterion is usually adopted for an appropriate mass scaling factor. However, to get closer to real machining processes, there is tendency of simulation with higher cutting speed considering more complicated factors, and the selection of mass scaling factor in this situation is difficult and computationally intensive. To solve this problem, this study aims to propose an efficient method of appropriately selecting mass scaling factor, which is upon the kinetic-to-internal energy ratio in the beginning stage of simulation. Through direct relationship between kinetic energy and cutting speed, the selection method applies under different cutting speeds; with the focus on the beginning stage of calculation, the proposed method requires little calculating work. By verification, such advantages are clearly presented with obviously improved calculating efficiency and limited error. What’s more, a set of empirical values of mass scaling factor suitable for different cutting speeds are provided for reference. The findings of this study could make great contributions in facilitating the development of 3D microscopic cutting simulation method of CFRP.